Friday, March 4, 2011

UGM Students Found Avian Influenza Vaccine

Through intensive research, a student at the Faculty of Veterinary Medicine, Gadjah Mada University discovered antiviral bird flu (avian influenza) H5N1.

Antivirus which has up to 87% level of effectiveness, according to its inventor, Arnita Prastiwi, made with fruit crown god (Phaleria macrocarpa) which are found in Indonesia.

Its success created the antiviral avian flu, the gained recognition in the competition of Scientific and Technological Society of Indonesia (MITI) Paper Challenge 2011 which was held January 29 last. Student generation of 2007 I won thanks to propose a series of studies contained in scientific papers berjudul infusion Extracts Antiviral Activity Test Mahkota Dewa (Phaleria macrocarpa) In ovo In Replication Inhibition of H5N1 virus vaccine Organic As Pioneer in Asia.

He managed to set aside 96 other papers from all over Indonesia. Told reporters on Thursday (3 / 3), confessed Artina uneasy with the phenomenon of the spread of AI virus in Indonesia who have been eating quite a lot of casualties.

According to him, farms and farmers and workers must be saved by pressing the spread of the H5N1 virus. According to him, was already there antivirus for avian influenza H5N1 in circulation, but because the price is quite high, difficult to reach small and medium farmers.

In addition, according to him, antivirus on the market do not use local materials. He explained that, after doing research, eventually producing a classified antiviral herbs and cheap. "With natural or herbal ingredients negative impacts can be minimized," he said.

According to him, the price can be offered even be cheaper. He called, antivirus creations can be sold at Rp75.000 per 100 doses, while outstanding during the average sale price of Rp200.000 per 100 doses.

"There is a difference amounting to Rp125.000 per 100 doses. It's profitable for the farmer," he said.

It is said, Â god crowns, local potential of Indonesia, Â which has been scientifically proven to increase endurance as antivirus AI.

 "The content of saponins in the fruit crown beneficial god other than to boost the immune system and vitality can also be used as an antibacterial and antiviral," he said.

To get the compound saponin, Artina gods crown fruit extract through distillation. How to make antivirus an extract from the crown of god begins with a weighting according to the dosage required. For a dose of 10 ml dry god crowns needed 100 grams per 100 ml of water or the multiplication of 100 grams per 1000 ml.

"Next step is to get the extract distillation? She said at the Laboratory of the Faculty of Veterinary Medicine. Extract the god crowns were then tested for levels of saponin content in the laboratory LPPT UGM.

She did the test 10 ml of saponin content in LPPT UGM. According to him, extract crown god must contain saponin content of 10%. The result of this diperoleh saponins which are used as raw material that is as a solvent suspense AI. Then viral antigens used as vaccine is 0.2 ml extract gods crown.

At first, spoken Artina, tests conducted on 30 embryonated chicken eggs. From the test results are known egg AI virus and given tambahan saponins extract fruit 10% of the crown of the god 0.2 ml after incubation for 35 days found no dead embryos, healthy and without scarring.
While eggs injected a higher dose of 15 percent and 20 percent, turned out all the embryos die with a form of bleeding throughout the body, dwarfism, and alantois turbid fluid.

"As many as 10% is the best result to prevent the bird flu virus. This proves that the saponin concentration used should be appropriate because the can cause poisoning if given in large doses,"  she said.

Once proven safe in the egg, the couple's daughter and Wartinah Sugita is testing this on chickens aged less than 21 days and the results are quite encouraging. Chickens that have been vaccinated not one that died.

The results of this study according to the plan will also be presented at the international seminar held in Japan AMSTECS on March 19 to 20 mendatang. and vitality of the immune system can also be used as an antibacterial and antiviral avian influenza. (OL-12)
Tags  "Avian Influenza , Avian Influenza Vaccine, Birds, Asia, Japan Avian Influenza, antiviral bird flu H5N1 "